NIOX takes Nitric Oxide supplementation to a new level by being the first and only product to utilize superior liquid capsules as a delivery system. The unique liquid capsule design of NIOX offers enhanced absorption and bio-availability, two critical factors in achieving optimum results.
In addition to that NIOX utilizes Arginine Ethyl Ester HCL as an advanced form of Arginine to generate a maximum amount of Nitric Oxide.
KEY BENEFITS:
- Dilates coronary arteries
- Vascular relaxation
- Relaxes gastrointestinal smooth muscle
- Improved memory, enhanced neurotransmission
- Unparalleled muscle growth and muscle fitness
- Improved erection
INGREDIENTS:
Arginine Ethyl Ester HCL 3000mg
Liquid Nitric Oxide Delivery System 3000mg
Sesame Oil
Oleic Acid
R-ALA
ATP
L-Norvaline
Calcium Phosphate
NIOX Other Ingredients:
Other Ingredients: Gelatin as capsule shell material.
Recommended Use
As a dietary supplement, For optimum results use NIOX every day. Stay well hydrated and drink at least 72oz. of water on a daily basis. Always take NIOX on an empty stomach approx. 30 minutes before a meal or workout as food or a full stomach will diminish the effects of this product.
Biological functions
In the body, nitric oxide is synthesized from arginine and oxygen by various nitric oxide synthase (NOS) enzymes and by sequential reduction of inorganic nitrate.
The endothelium (inner lining) of blood vessels use nitric oxide to signal the surrounding smooth muscle to relax, thus dilating the artery and increasing blood flow; bodybuilders use this to achieve a more "ripped", vascular look. This underlies the action of nitroglycerin, amyl nitrate and other nitrate derivatives in the treatment of heart disease: The compounds are converted to nitric oxide (by a process that is not completely understood), which in turn dilates the coronary artery (blood vessels around the heart), thereby increasing its blood supply. Nitric oxide also plays a role in erection of the penis, and explains the mechanism of sildenafil (Viagra®). The effects of the recreational drugs known as poppers are also thought to be due to nitric oxide.
Macrophages, certain cells of the immune system, produce nitric oxide in order to kill invading bacteria. Under certain conditions, this can backfire: Fulminant infection (sepsis) causes excess production of nitric oxide by macrophages, leading to vasodilatation (widening of blood vessels), probably one of the main causes of hypotension (low blood pressure) in sepsis.
Nitric oxide also serves as a neurotransmitter between nerve cells. Unlike most other neurotransmitters that only transmit information from a presynaptic to a postsynaptic neuron, the small nitric oxide molecule can diffuse all over and can thereby act on several nearby neurons, even on those not connected by a synapse. It is conjectured that this process may be involved in memory through the maintenance of long-term potentiation. Nitric oxide is an important non-adrenergic, non-cholinergic (NANC) neurotransmitter in various parts of the gastrointestinal tract. It causes relaxation of the gastrointestinal smooth muscle. In the stomach it increases the capacity of the fundus to store food/fluids.
Production of NO also plays a role in development and maintenance of erection by stimulating the production of intracellular cGMP in the smooth muscle cells surrounding the blood vessels supplying the corpus cavernosum; through relaxation of these muscles, more blood can flow in. This is the biological basis of sildenafil (Viagra), which works to inhibit the enzyme PDE5 that lowers the cGMP concentration by converting it to GMP. The high levels of cGMP that result lead to vasodilation and hence erection.
Dietary nitrate is also an important source of nitric oxide in mammals. Green, leafy vegetables and some root vegetables (such as beetroot) have high concentrations of nitrate. When eaten and absorbed into the bloodstream nitrate is concentrated in saliva (about 10 fold) and is reduced to nitrite on the surface of the tongue by a biofilm of commensal facultative anaerobic bacteria. This nitrite is swallowed and reacts with acid and reducing substances in the stomach (such as ascorbate) to produce high concentrations of nitric oxide. The purpose of this mechanism to create NO is thought to be both sterilisation of swallowed food, to prevent food poisoning and to maintain gastric mucosal blood flow. A similar mechanism is thought to protect the skin from fungal infections, where nitrate in sweat is reduced to nitrite by skin commensal organisms and then to NO on the slightly acidic skin surface.
The discovery of the biological functions of nitric oxide in the 1980s came as a complete surprise and caused quite a stir. Nitric oxide was named "Molecule of the Year" in 1992 by the journal Science, a Nitric Oxide Society was founded, and a scientific journal devoted entirely to nitric oxide was created. The Nobel Prize in Physiology or Medicine in 1998 was awarded to Ferid Murad, Robert F. Furchgott, and Louis Ignarro for the discovery of the signalling properties of nitric oxide. It is estimated that yearly about 3,000 scientific articles about the biological roles of nitric oxide are published.
For Circulatory Support:
6 Liqui-Caps Per Day. Two times three caps.
For Male Athletes Up to 210 lbs:
8 Liqui-CapsPer Day. Take 4 Liqui-Caps with10oz. of water 30 minutes before breakfast and repeat 30 minutes before lunch. On training days take one of your daily servings 30 minutes before working out.
For Male Athletes Over 210 lbs:
12 Liqui-Caps Per Day. Take 4 Liqui-Caps with 10oz. of water 30 minutes before breakfast and repeat 30 minutes before lunch and 30 minutes before dinner. On training days take one of your daily servings 30 minutes before working out.
For Female Athletes Up to 130 lbs:
6 Liqui-Caps Per Day. Take 3 Liqui-Caps with 10oz. of water 30 minutes before breakfast and repeat 30 minutes before lunch. On training days take one of your daily servings 30 minutes before working out.
For Female Athletes Over 130 lbs:
8 Liqui-Caps Per Day. Take 4 Liqui-Caps with 12oz. of water 30 minutes before breakfast and repeat 30 minutes before lunch. On training days take one of your daily servings 30 minutes before working out.
